Bone Marrow Score (NT-FLASH, 新台灣之光)

  Parameters Findings Points Check
Neutropenia Absolute neutrophil count <2000/µL 1.0
Thrombocytopenia Platelets <100 x103/µL 2.0
hyperFerritinemia Ferritin >1000 ng/mL 5.5
Leukoerythroblastic PB smear Leucoerythroblastic changes 6.0
Anemia Haemoglobin <10 g/dL 1.5
Splenomegaly Splenomegaly Yes 4.0
LDH elevated Lactic dehydrogenase >upper limit of normal 1.5
       
References
  1. Wang HY, Yang CF, Chiou TJ, Yang SH, Gau JP, Yu YB, Liu CY, Liu JH, Chen PM, Hsu HC, Fung CP, Tzeng CH, Hsiao LT.* A "bone marrow score" for predicting hematological disease in immunocompetent patients with fevers of unknown origin. Medicine (Baltimore). 2014 Dec;93(27):e243. PubMed
  2. Wang HY, Yang CF, Chiou TJ, Yang SH, Gau JP, Yu YB, Chen PM, Hsu HC, Fung CP, Lin HY, Tzeng CH, Liu JH, Hsiao LT.* Risk of hemophagocytic lymphohistiocytosis in adults with fevers of unknown origin: the clinical utility of a new scoring system on early detection. Hematol Oncol. 2017 Dec;35(4):835-844. doi: 10.1002/hon.2333. Epub 2016 Jul 28. PubMed
  3. Wang HY,* Yang CF, Chiou TJ, Gau JP, Chen PM, Tsai CY, Hsu HC, Wang FD, Liu JH, Hsiao LT.* Primary bone marrow lymphoma: A hematological emergency in adults with fever of unknown origin. Cancer Med. 2018 Aug;7(8):3713-3721. doi:10.1002/cam4.1669. Epub 2018 Jul 9. PubMed